NobleReach Foundation

The Malaghan Institute

Providing Medical Grade Hookworms to Develop Ground-Breaking Therapies for Debilitating Diseases

*DARPA Funded, Therapeutics

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Company Description

This biotechnology startup spinning out of the Malaghan Institute is specializing in the field of helminth (hookworm) therapy and GMP production. The company will draw on the cutting-edge research activities of the Malaghan Institute of Medical Research to position itself as the world’s first medical grade hookworm provider.

Helminth therapy is a groundbreaking therapy for the treatment of allergic, metabolic, and gastrointestinal diseases and potentially others. Around the globe, helminth technologies are being studied for their ability to modulate the immune system with extremely promising results. However, no production technology has been available that would enable regulatory approved manufacturing, distribution, and human hosting of hookworm as a therapeutic intervention.

The team have developed a unique suite of proprietary technologies that will allow GMP manufacturing of helminth at scale to move the hookworm out of the lab and into practical, real-world applications.

Short Job Description

Working with a team of renowned researchers, the company is commercializing a suite of helminth products, to provide medical grade hookworms that can be advanced through regulatory approval processes.

The team is seeking an experienced therapeutics professional with strong networks with regulatory agencies, patient advocacy groups/foundations, and industry stakeholders. This entrepreneur role will support the company’s senior management team in-market and play a key role in guiding business strategy and planning.

Key Tasks:

  • Identify and prioritize commercial opportunities for the startup’s suite of therapeutic helminths and delivery approaches.
  • Determine the differentiation, sustainability, and longevity of the platform, and component technologies, that have been, or will be, developed to produce therapeutic worms as well as associated delivery mechanisms (transdermal; oral).
  • Define the product portfolio and corresponding pipeline of products.
  • Lead business development activities to engage key US stakeholders in regulatory, clinical and commercial discussions to inform early-stage business strategy and focus.
  • Identify requirements required to gain regulatory approval for the unique helminth platform and specific human health applications and cGMP manufacturing requirements.
  • Identify key strategic investor groups and ensure company activities align with their investment requirements.
  • Manage investor discussions and prepare documentation required to lead a successful investment round

This is a fully remote, part-time position with the possibility of a full-time leadership role in the future.

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